PROGRESS

2024

  1. Nguyen T.P., *Otani T., Tsutsumi M., Kinoshita N., Fujiwara S., Nemoto T., Fujimori T. and *Furuse M.
    "Tight junction membrane proteins regulate the mechanical resistance of the apical junctional complex"
    Journal of Cell Biology 2024 May 6;223(5):e202307104
    [Pubmed] [プレスリリース]
  2. Kitamura D., Taniguchi K., Nakamura M. and *Igaki T.
    "In vivo evidence for homeostatic regulation of ribosomal protein levels in Drosophila"
    Cell Structure and Function 2024 Feb 16;49(1):11-20
    [Pubmed]

2023

  1. Zou J., Anai S., Ota S., Ishitani S., Oginuma M and *Ishitani T.
    "Determining zebrafish dorsal organizer size by a negative feedback loop between canonical/non-canonical Wnts and Tlr4/NFκB"
    Nature Communications 2023 Nov 8;14(1):7194
    [Pubmed] [プレスリリース]
  2. Kira A., Tatsutomi I., Saito K., Murata M., Hattori I., Kajita H., Muraki N., Oda Y., Satoh S, Tsukamoto Y., Kimura S., Onoue K., Yonemura S., Arakawa S., Kato H., *Hirashima T., and *Kawane K.
    "Apoptotic extracellular vesicle formation via local phosphatidylserine exposure drives efficient cell extrusion"
    Developmental Cell 2023 Jul 24;58(14):1282-1298.e7
    [Pubmed] [プレスリリース]
  3. *Kawamata M., *Suzuki H., Kimura R., and *Suzuki A.
    "Optimization of Cas9 activity through the addition of cytosine extensions to single-guide RNAs"
    Nature Biomedical Engineering 2023 May;7(5):672-691
  4. *Yabe T., *Uriu K., and *Takada S.
    "Ripply suppresses Tbx6 to induce dynamic-to-static conversion in somite segmentation"
    Nature Communications 2023 Apr 13;14(1):2115
    [Pubmed] [プレスリリース]
  5. Hatakeyama Y., *Saito N., Mii Y., Takada R., Shinozuka T., Takemoto T., Naoki H., and *Takada S.
    "Intercellular exchange of Wnt ligands reduces cell population heterogeneity during embryogenesis"
    Nature Communications 2023 Apr 6;14(1):1924
    [Pubmed] [プレスリリース]
  6. *Taniguchi K. and *Igaki T.
    "Sas-Ptp10D shapes germ-line stem cell niche by facilitating JNK-mediated apoptosis"
    PLoS Genetics 2023 Mar 27;19(3):e1010684
    [Pubmed] [プレスリリース]
  7. Hoshino R., Sano H., Yoshinari Y., Nishimura T., and *Niwa, R.
    "Circulating fructose regulates a germline stem cell increase via gustatory receptor-mediated gut hormone secretion in mated Drosophila"
    Science Advances 2023 Feb 24;9(8):eadd5551
    [Pubmed] [プレスリリース]

2022

  1. Wang Z., Xia X., Li J., and *Igaki T.
    "Tumor elimination by clustered microRNAs miR-306 and miR-79 via non-canonical activation of JNK signaling"
    eLife 2022 Oct 12;11:e77340
    [Pubmed]
  2. Kuromiya K., Aoki K., Ishibashi K., Yotabun M., Sekai M., Tanimura N., Iijima S., Ishikawa S., Kamasaki T., Akieda Y., Ishitani T., Hayashi T., Toda S., Yokoyama K., Lee C.G., Usami I., Inoue H., Takigawa I., Gauquelin E., Sugimura K., Hino N., and *Fujita Y.
    "Calcium sparks enhance the tissue fluidity within epithelial layers and promote apical extrusion of transformed cells"
    Cell Reports 2022 Jul 12;40(2):111078
    [Pubmed]
  3. Oginuma M., Nishida M., Ohmura-Adachi T., Abe K., Ogamino S., Mogi C., Matsui H., and *Ishitani T.
    "Rapid reverse genetics systems for Nothobranchius furzeri, a suitable model organism to study vertebrate aging"
    Scientific Reports 2022 Jul 8;12(1):11628
    [Pubmed] [プレスリリース]
  4. Suzuki H., Aoki K., Kurosawa K., Imagawa K., Ohto T., Yamada M., Takenouchi T., *Kosaki K., and *Ishitani T.
    "De novo non-synonymous CTR9 variants are associated with motor delay and macrocephaly: human genetic and zebrafish experimental evidence"
    Human Molecular Genetics 2022 Nov 10;31(22):3846-3854
    [Pubmed]
  5. Mori Y., Shiratsuchi N., Sato N., Chaya A., Tanimura N., Ishikawa S., Kato M., Kameda I., Kon S., Haraoka Y., Ishitani T., and *Fujita Y.
    "Extracellular ATP facilitates cell extrusion from epithelial layers mediated by cell competition or apoptosis"
    Current Biology 2022 May 23;32(10):2144-2159.e5
    [Pubmed]
  6. Haraoka Y., Akieda Y., Nagai Y., Mogi C., and *Ishitani T. 
    "Zebrafish imaging reveals TP53 mutation switching oncogene-induced senescence from suppressor to driver in primary tumorigenesis"
    Nature Communications 2022 Mar 18;13:1417
    [Pubmed] [プレスリリース]
  7. Nagata R., Akai N., Kondo S., Saito K., Ohsawa S., and *Igaki T.
    "Yorkie drives supercompetition by non-autonomous induction of autophagy via bantam microRNA in Drosophila"
    Current Biology 2022 Mar 14;32(5):1064-1076.e4
    [PubMed][プレスリリース]
  8. Lohani S., Funato Y., Akieda Y., Mizutani K., Takai Y., Ishitani T., and *Miki H.
    "A novel role for PRL in regulating epithelial cell density by inducing apoptosis at confluence"
    Journal of Cell Science 2022 Jan 15;135(2):jcs258550
    [PubMed]

2021

  1. Kato T., Liu N., Morinaga H., Asakawa K., Muraguchi T., Muroyama Y., Shimokawa M., Matsumura H., Nishimori Y., Tan L. J., Hayano M., Sinclair D. A., Mohri Y. and *Nishimura E. K.
    "Dynamic stem cell selection safeguards the genomic integrity of the epidermis"
    Developmental Cell 2021 Dec 20;56(24):3309-3320.e5
    [PubMed][プレスリリース]
  2. Ishii M., Tateya T., Matsuda M. and *Hirashima T.
    "Stalling interkinetic nuclear migration in curved pseudostratified epithelium of developing cochlear duct"
    Royal Society Open Science 2021 Dec 8;8(12):211024
    [PubMed]
  3. Ochi N., Nakamura M., Nagata R., Wakasa N., Nakano R. and *Igaki T.
    "Cell competition is driven by Xrp1-mediated phosphorylation of eukaryotic initiation factor 2α"
    PLoS Genetics 2021 Dec 6;17(12):e1009958
    [PubMed] [プレスリリース]
  4. *Oda Y., Takahashi C., Harada S., Nakamura S., Sun D., Kiso K., Urata Y., Miyachi H., Fujiyoshi Y., Honigmann A., Uchida S., Ishihama, Y. and Toyoshima, F.
    "Discovery of anti-inflammatory physiological peptides that promote tissue repair by reinforcing epithelial barrier formation"
    Science Advances 2021 Nov 19;7(47):eabj6895
    [PubMed] [プレスリリース]
  5. Maehara K., Tomimatsu K., Harada A., Tanaka K., Sato S., Fukuoka M., Okada S., Handa T., Kurumizaka H., Saitoh N., Kimura H. and *Ohkawa Y.
    "Modeling population size independent tissue epigenomes by ChIL-seq with single thin sections"
    Molecular Systems Biology 2021 Nov;17(11):e10323
    [PubMed] [プレスリリース]
  6. Cong B., Nakamura M., Sando Y., Kondo T., Ohsawa S. and *Igaki T.
    "JNK and Yorkie drive tumor malignancy by inducing L-amino acid transporter 1 in Drosophila"
    PLoS Genetics 2021 Nov 15;17(11):e1009893
    [PubMed]
  7. Kamasaki T., Miyazaki Y., Ishikawa S., Hoshiba K., Kuromiya K., Tanimura N., Mori Y., Tsutsumi M., Nemoto T., Uehara R., Suetsugu S., Itoh T. and *Fujita Y.
    "FBP17-mediated finger-like membrane protrusions in cell competition between normal and RasV12-transformed cells"
    iScience 2021 Aug 18;24(9):102994
    [PubMed]
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